Axcel Cefuroxime Warnings

Serious and occasionally fatal hypersensitivity reactions (including anaphylactoid and severe cutaneous adverse reactions) have been reported in patients receiving therapy with beta-lactams. Before initiating therapy with Axcel Cefuroxime, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, carbapenems or other beta-lactam agents. If an allergic reaction occurs, Axcel Cefuroxime must be discontinued immediately and appropriate alternative therapy instituted.
Capsule: This product should be given cautiously to penicillin-sensitive patients. Antibiotics should be administered with caution to any patient who has demonstrated some form of allergy, particularly to drugs.
Serious acute hypersensitivity reactions may require epinephrine and other emergency measures. Pseudomembranous colitis has been reported with nearly all antibacterial agents, including cefuroxime, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents.