Axcel Cefuroxime Side Effects

Tablet and Oral suspension: Adverse reaction to Cefuroxime Axetil is generally mild and transient in nature.
Capsule and Oral suspension: Gastrointestinal disturbances, including diarrhoea, nausea and vomiting, have occurred in some patients receiving Cefuroxime Axetil. As with other broad-spectrum antibiotics, there have been reports of pseudomembranous colitis. Headache has also been reported. There have been rare reports of erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, thrombocytopenia, leucopenia, jaundice, haemolytic anaemia and hypersensitive reactions including skin rashes, urticaria, pruritus, drug fever, serum sickness and very rarely anaphylaxis. Eosinophilia and transient increases of hepatic enzyme levels (ALT and AST) have been noted during Cefuroxime therapy.
Tablet: The incidence of adverse reactions associated with Cefuroxime Axetil may vary according to the indication. The following side effects have been observed: Infections and infestations: overgrowth of candida.
Blood and lymphatic system disorders: Eosinophilia, Positive Coombs test, thrombocytopenia, leukopenia (sometimes profound) and Haemolytic anaemia. Cephalosporin tend be absorbed onto the surface of red cells membranes and react with antibodies directed against the drug to produce a positive Coombs test (interfere with cross-matching of blood) and very rarely haemolytic anaemia.
Immune system disorders: Hypersensitivity reactions including rashes, urticaria, pruritus, drug fever, serum sickness, and anaphylaxis.
Nervous system disorders: Headache, dizziness.
Gastrointestinal disorders: Gastrointestinal disturbances including diarrhoea, nausea, abdominal pain, vomiting, and Pseudomembranous colitis.
Hepatobiliary disorders: Transient increases of hepatic enzyme levels, [ALT (SGPT), AST (SGOT), LDH], jaundice (predominantly cholestatic), and hepatitis.
Skin and subcutaneous tissue disorders: Erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (exanthematic necrolysis), see immune system disorders as previously mentioned.
Axcel Cefuroxime-500 mg Tablet may cause severe allergy and serious skin reactions. Stop using Axcel Cefuroxime-500 mg Tablet and seek medical assistance immediately if the patient experiences any of the following symptoms: skin reddening, blisters, rash, fever, sore throat or eye irritation.
Oral suspension: There have been rare reports of thrombocytopenia and leucopenia (sometimes profound). As with other cephalosporins, jaundice has been reported very rarely. Cephalosporins as a class tend to be absorbed onto the surface of red cells membranes and react with antibodies directed against the drug to produce a positive Coombs' test (which can interfere with cross-matching of blood) and very rarely haemolytic anaemia.