Axcel Cefuroxime Drug Interactions

Drugs which reduce gastric acidity may result in a lower bioavailability of this antibiotic compared with that of the fasting state and tend to cancel the effect of enhanced absorption after food.
Cefuroxime may cause false negative results in the ferricyanide test, it is recommended that either glucose oxidase or hexokinase method are used to determine blood/plasma glucose levels in patients receiving Cefuroxime. The antibiotic does not interfere the alkaline picrate assay for creatinine.
Capsule: Drug-lab Interaction: A positive Coombs' test has been reported during treatment with cephalosporins this phenomena can interfere with cross-matching of blood. Cefuroxime does not interfere in enzyme based tests for glycosuria. Slight interference with copper reduction methods (Benedict's Fehling's, Clinitest) may be observed. However, this should not lead to false positive results, as may be experienced with some other cephalosporins.
Tablet: Similar with other antibiotics, Axcel Cefuroxime-500 mg Tablet may affect the gut flora, leading to lower oestrogen reabsorption and reduced efficacy of combined oral contraceptives.