Timo-COMOD Dosage/Direction for Use

For ocular use.
The usual starting dose is one drop of 0.25% Timolol solution in the affected eye(s) twice daily. If required, the dose can be increased to 1 drop of 0.5% Timolol solution twice daily. Timo-COMOD 0.5% eye drops are instilled into the conjunctival sac and are suitable for long-term therapy.
For a small proportion of patients, 1 drop of 0.1% Timolol solution, twice a day may be satisfactory. If the clinical response is not adequate with 0.1% solution, the dosage should be increased to 1 drop of 0.25% in the affected eye(s) twice daily.
Newborns and infants: Some cases of apnoea in newborns have been reported, which may have been caused by the immaturity of these patients. Application to premature babies and newborns is not recommended because of the possible central nervous effects.
Due to much higher dosages, based on body weight, in newborns and infants, there is a higher chance of systemic side-effects. Therefore, accurate diagnosis is imperative in infants; the patients have to be observed carefully to detect any sign of systemic beta-receptor blockage.