Adult & childn >12 yr 1-2 g once daily IM/IV, up to 4 g daily. Neonate & childn (15 days-12 yr) 20-80 mg/kg once daily. Neonate (w/in 14 days) 25-50 mg/kg once daily. MeningitisNeonate & childn 100 mg/kg once daily. Max: 4 g/day. Duration of treatment for N. meningitidis 4 days, H. influenzae 6 days, S. pneumococcus 7 days. Gonorrhea 250 mg IM. Peri-op prophylaxis 1-2 g given 30-90 min before surgery.
Patients w/ history of allergy to drugs. Patients whose family is susceptible to cause the allergy symptoms eg, bronchial asthma, eruption & urticaria.
Severe renal disorder. Patients who cannot ingest orally or parenteral patients, elderly & patients w/ systemic bad condition. Perform regular liver, renal, hematologic tests.