Medzyme/Medzyme Vial Dosage/Direction for Use

Medzyme: Suspension 125 mg and 250 mg: Children (more than 6 months): 125 mg: 1 teaspoonful twice daily.
250 mg (maximum): 2 teaspoonful daily.
Over 2 years old: 250 mg: 1 teaspoonful twice daily.
500 mg (maximum): 2 teaspoonful daily.
Or as prescribed by the physician.
500mg Film-coated Tablet: Adults: 500 mg twice daily.
Or as prescribed by the physician.
Medzyme Vial: Adults: For more severe infections, this dose should be increased to 1.5 g three or four times a day, IV injection. Total dose is 3g-6g daily.
Infants and Children: 30-100 mg/kg/day, given as three or four divided doses. A dose of 60 mg/kg/day will be appropriate for most infections.
Neonates: 30-100 mg/kg/day, given as two or three divided doses. In the first week of life, the serum half-life of Cefuroxime can be three to five times that in adults.
Gonorrhea: 1.5 g should be given as a single dose. This may be given as 2 x 750 mg injections into different sites, e.g. each buttock.
Prophylaxis: The usual dose is 1.5 g IV with induction of anesthesia for abdominal, pelvic and orthopedic operations, but may be supplemented with two 750 mg IM doses eight and sixteen hours later. In cardiac, pulmonary, esophageal and vascular operations, the usual dose is 1.5 g IV with induction of anesthesia continuing with 750 mg three times a day, IM t.i.d. for a further 24 to 48 hours. In total joint replacement, 1.5 g cefuroxime powder may be mixed dry with the methyl methacrylate cement.
Meningitis: Adults: 3 g I.V. every eight hours.
Infants and Children: 200 to 240 mg/kg/day I.V in three or four divided doses. This dosage may be reduced to 100 mg/kg/day IV after three days or when clinical improvement occurs.
Neonates: The initial dosage should be 100 mg/kg/day I.V. A reduction to 50 mg/kg/day IV may be made when clinically indicated.