Medzyme/Medzyme Vial Adverse Reactions

Medzyme: As with other cephalosporins, there have been rare reports of erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (exanthematic necrolysis) and hypersensitivity reactions including skin rashes, urticaria, pruritus, interstitial nephritis, drug fever, serum sickness and very rarely anaphylaxis.
Some patients receiving cefuroxime axetil have experienced gastrointestinal disturbances including diarrhea, nausea and vomiting. As with other broad spectrum antibiotics, there have been occasional reports of pseudomembranous colitis. Headache has also been reported.
There have been rare reports of thrombocytopenia and leucopenia. As with other cephalosporins, jaundice has been reported very rarely.
Medzyme Vial: Common: Local irritation and thrombophlebitis following intravenous injection, diarrhea, maculopapular rash.
Less common: anaphylactic reaction, Candida infection, eosinophilia, leucopenia, neutropenia, nausea, vomiting, urticaria, pruritus.
Rare: fever, haemolytic anemia, pseudomembranous colitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, cholestatic jaundice, slight elevation of AST, ALT, and nephrotoxicity with transient elevations of blood urea nitrogen/creatinine, interstitial nephritis.
Inform the doctor or pharmacist in case of any adverse reactions related to drug use.