Advertisement
Advertisement
Medzyme/Medzyme Vial

Medzyme/Medzyme Vial

cefuroxime

Manufacturer:

Medhaus

Distributor:

Medhaus
Concise Prescribing Info
Contents
Medzyme Cefuroxime axetil. Medzyme Vial Cefuroxime Na
Indications/Uses
Susceptible infections eg, bone & joint infections, bronchitis (& other lower resp tract infections), gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis, skin infections (including soft-tissue infections), surgical infection (prophylaxis) & UTI.
Dosage/Direction for Use
Medzyme FC tab Adult 500 mg bid. Medzyme granules for oral susp Childn >2 yr 250 mg bid. Max: 500 mg daily, >6 mth 125 mg bid. Max 250 mg daily. Medzyme Vial Adult Severe infections 1.5 g tid or qid. Total dose: 3-6 g daily. Childn & infant 30-100 mg/kg/day as 3 or 4 divided doses. Neonate 30-100 mg/kg/day as 2 or 3 divided doses. Gonorrhea 1.5 g as a single dose. Prophylaxis: Abdominal, pelvic & orthopedic operations 1.5 g IV w/ induction of anesth, may be supplemented w/ two 750 mg dose IM 8 & 16 hr later. Cardiac, pulmonary esophageal & vascular operations 1.5 g IV w/ induction of anesth continuing w/ 750 mg IM tid for a further 24-48 hr. Total joint replacement 1.5 g mixed dry w/ methyl methacrylate cement. Meningitis Adult 3 g IV every 8 hr. Childn & infant 200-240 mg/kg/day IV in 3 or 4 divided doses. May be reduced to 100 mg/kg/day IV after 3 days or when clinical improvement occurs. Neonate Initially 100 mg/kg/day IV. May be reduce to 50 mg/kg/day when clinically indicated.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to cephalosporins & penicillins.
Special Precautions
GI disease, particularly colitis. Pregnancy & lactation. Medzyme Vial Patients w/ transient or persistent renal insufficiency. Overgrowth of non-susceptible organisms during prolonged use. Interrupt treatment if severe superinfection occurs. Pseudomembranous colitis.
Adverse Reactions
Medzyme Erythema multiforme, SJS, TEN. Hypersensitivity reactions including skin rashes, urticaria, pruritus, interstitial nephritis, drug fever, & serum sickness. GI disturbances including diarrhea, nausea & vomiting. Pseudomembranous colitis. Headache. Medzyme Vial Local irritation & thrombophlebitis following IV inj, diarrhea, maculopapular rash.
Drug Interactions
Reduced renal clearance w/ probenecid. Medzyme Vial May increase renal disorder w/ furosemide or aminoglycoside antibiotics.
MIMS Class
Cephalosporins
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Medzyme FC tab 500 mg
Packing/Price
40's (P2,600/pack)
Form
Medzyme granules for oral susp 125 mg/5 mL
Packing/Price
50 mL x 1's (P275/bottle)
Form
Medzyme granules for oral susp 250 mg/5 mL
Packing/Price
50 mL x 1's (P395/bottle)
Form
Medzyme Vial powd for inj 750 mg
Packing/Price
10 × 1's (P3,200/box)
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement