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Doctors are advised to titrate the required dosage according to individual patient's response during initial administration.
The dose should be adjusted according to the individual patient's response, commencing with 40-80 mg daily and increasing until adequate control is achieved. A single dose should not exceed 160 mg and when higher doses are required, a twice-daily split dosage is advised and should be divided according to the main meals of the day. In the majority of cases, 2 tablets/day with meals, (1 tablet with breakfast, 1 tablet with dinner).
For the elderly diabetic, the starting dose should be ½ tablet in the morning and ½ tablet in the evening.
Route of Administration: Oral.
