Mefenamic Acid may give rise to occasional gastrointestinal upsets or rashes. Gastrointestinal haemorrhage may rarely occur. Other haematological effects include haemolytic anaemia, agranulocytosis, pancytopenia, thrombocytopenia, thrombocytopenic purpura and bone marrow aplasia.
The occurrence of diarrhoea or skin rash is an indication for discontinuing treatment.
Skin and Subcutaneous Tissue Disorders: Generalised bullous fixed drug eruption (GBFDE).