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Concomitant administration of cisplatin with Thioctic acid 600 mg/50 ml, solution for infusion leads to loss of efficacy of cisplatin.
The blood-sugar lowering effect of insulin or oral anti-diabetics may be reinforced.
Close monitoring of blood sugar levels is indicated during thioctic acid therapy, particularly during the initial phase. In individual cases, to avoid hypoglycaemia, it is necessary to reduce the insulin dose or the dose of the oral anti-diabetics.
Regular intake of alcohol represents a significant risk factor for the development and progression of neuropathic pathologies and thus can impair the success of treatment with Thioctic acid 600 mg/50 ml, solution for infusion. Patients with diabetic polyneuropathy are recommended to avoid the consumption of alcohol. This also applies to therapy-free intervals.
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