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Incompatibilities: Thioctic acid reacts in vitro with metal ion complexes (e.g. with cisplatin) and with sugar molecules (e.g. levulose solutions); it forms low solubility complex.
Furthermore, Thioctic acid 600 mg/50 ml, solution for infusion is incompatible with glucose solution, Ringer solution and with solutions that are known to react with sulfhydryl-groups or disulfide bridges.
Thioctic acid 600 mg/50 ml, solution for infusion product can be diluted with physiological saline solution (0.9% sodium chloride solution) when administered as an infusion.
Special precautions for disposal and other handling: Thioctic acid 600 mg/50 ml, solution for infusion product can be diluted with physiological saline solution (0.9% sodium chloride solution) when administered as an infusion.
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