Thiogamma I.V. Dosage/Direction for Use

Posology: Adults: In the case of severe (very pronounced) symptoms of diabetic polyneuropathy in adults, the intravenous administration of one daily dose of 600 mg thioctic acid is recommended (equivalent to one ampoule of Thioctic acid 600 mg/50 ml, solution for infusion).
Peadiatric population: Thioctic acid 600 mg/50 ml, solution for infusion should not be used in children, as there is no clinical experience in this age group.
Hepatic impairment: Experience is limited in patients with hepatic impairment. Therefore, Thioctic acid 600 mg/50 ml, solution for infusion should be used with caution in these patients.
Method and Duration of administration: In adults, an initial treatment phase of 2-4 weeks for once daily. Parenteral administration (intravenous infusion) is recommended. After completion of the infusion therapy, daily use of 600 mg thioctic acid film-coated tablets is recommended.
Adults should receive a slow intravenous infusion with the contents being administered over at least 30 minutes. The infusion is done directly from the bottle using a standard infusion set and the provided light-protected suspension bag. The active substance is photosensitive and the infusion bottle should be removed from the carton box only shortly before administration. The minimum infusion time of 30 minutes must be ensured.
The product may be diluted with physiologic saline solution (0.9% Sodium chloride solution) only.