Aescin, diethylamine salicylate.
Reparil-Gel N is a transparent, colourless to slightly yellowish gel.
The active substances are: 100 g Reparil-Gel N contains: Aescin 1 g, Diethylamine salicylate 5 g.
Excipients/Inactive Ingredients: Polyacrylic acid, macrogol-6-caprylic acid glycerides, sodium edetate, trometamol, isopropanol, flavours.
Pharmacology: The target site of aescin is the vascular wall. In the case of inflammatory raised permeability, escin inhibits exudation by reducing extravasation of fluid into the tissue spaces, and it accelerates reabsorption of the existing oedema. The mechanism of action is based on a change in the permeability of the capillary openings involved. Furthermore, escin promotes capillary resistance, inhibits inflammatory processes and improves microcirculation.
Diethylamine salicylate (DEAS) has a pronounced analgesic effect. It penetrates freely through the skin and exerts its analgesic action in the depths of the affected area. The additional antiphlogistic action of DEAS enhances the anti-inflammatory effect of aescin and thus combats the causal factors of the course of disease.
Reparil-Gel N reduces swelling, inhibits inflammation and relieves pain.
Injuries with contusions, sprains, bruises, haematoma formation, tendinitis (inflammation of tendon sheaths).
Vertebral pain syndromes (intervertebral disk, nuchal pain, lumbago, sciatica).
Superficial phlebitis, varicose veins.
For vein care following injections or infusions.
Always use Reparil-Gel N exactly as specified in this monograph. Check with the doctor or pharmacist if unsure.
Recommended dose: The usual dose is: Unless otherwise directed by the doctor, apply Reparil-Gel N 2-3 times daily.
The maximum daily dose is 20 g of gel, equivalent to about 650 mg of salicylate. Diethylamine salicylate/escin gel should be allowed to dry on the skin for some minutes before a dressing is applied. Using an occlusive dressing is not recommended.
Mode of administration: Apply Reparil-Gel N to the affected area and spread it over the skin. It need not be rubbed in, but the patient may do this as wished.
If there are any further questions on the use of this medicine, ask the doctor or pharmacist.
Special populations: The use in children under the age of 12 years is not recommended.
No dose adjustment is necessary in the elderly population. No dose reduction is required in patients with impaired renal or liver function.
Overdose and treatment: No manifestation of overdosage or intoxication have been reported to date.
Reparil-Gel N should not be used: Hypersensitivity to the active substances and/or other ingredients in the formulation.
Reparil-Gel N should not be applied to broken skin (wounds), around the eyes, mucous membranes or skin areas which have been exposed to radiotherapy.
Read all of this monograph carefully because it contains important information.
This medicine is available without prescription. However, the patient still needs to use Reparil-Gel N carefully to get the best results from it.
Ask the pharmacist if the patient needs more information or advice.
See a doctor if symptoms worsen or do not improve.
If any of the side effects gets serious, or if the patient notices any side effects not listed in this monograph, tell the doctor or pharmacist.
No special precautions are required when using Reparil-Gel N.
As a preparation for topical applications, its use must be for external use only.
Patients hypersensitive to salicylates are at a greater risk of developing asthma attacks, local skin and mucosal swelling (Quincke's oedema) or urticaria than other patients. In these patients, diethylamine salicylate/escin must be used with caution and only under direct medical monitoring.
The contact with the eyes must be avoided.
This medicine contains as fragrances lavender oil and neroli oil/bitter orange flower oil with d-limonene, farnesol and linalool. These substances may cause allergic reactions.
There are no or limited amount of data from the use of Diethylamine salicylate/escin in pregnant women.
Animal studies are insufficient with respect to reproductive toxicity of the ingredients Diethylamine salicylate and escin. Diethylamine salicylate/escin is not recommended during pregnancy and breastfeeding. In particular, the use on large areas of the skin should be avoided.
It is unknown whether Diethylamine salicylate/escin is excreted in human milk. A risk to the suckling child cannot be excluded, therefore Diethylamine salicylate/escin is not recommended during breastfeeding. In particular, the application on breasts during breastfeeding should be avoided.
Like all medicines, Reparil-Gel N can cause side effects, although not everybody gets them.
Side effects' rating was based on the following frequency data: See table.
Click on icon to see table/diagram/image
Allergic cutaneous manifestations (i.e. itching and erythema) may arise in very rare cases.
If any of the mentioned side effects gets serious, or if the patient notices any side effects not listed in this monograph, tell the doctor or pharmacist.
Using Reparil-Gel N with other medicines: No interactions are known.
Tell the doctor or pharmacist if taking or have recently taken any other medicines, even non-prescription medicines.
Store below 30°C in dry place.
No other special storage conditions are required for this medicine.
M02AC - Preparations with salicylic acid derivatives ; Used in the topical treatment of joint and muscular pains.
Reparil-Gel N topical gel
10 g x 1's;20 g x 1's;40 g x 1's
Sign Out
Click on icon to see table/diagram/image
Continue with Google
Sign up with email
Already a member?
Sign in
