GynProgesterone Special Precautions

The treatment is not contraceptive, taken according to the recommended dosage and conditions of use.
Prior to taking hormone (and at regular intervals thereafter) each woman should be assessed.
A personal and family medical history should be taken and physical examination should include special reference to breast and pelvic organ as well as cervical cytology. Progesterone capsules should be used cautiously in patients such as with conditions that might be aggravated by fluid retention (e.g. cardiac disease, renal disease, epilepsy, migraine, asthma): in patients with a history of depression, diabetes, mild to moderate hepatic dysfunction, migraine.
Effects on the ability to drive and use machines: The risk of drowsiness and/or dizziness has been reported in relation to oral use of the medicinal product. People who have to drive and use machines should therefore be warned that this is possible.
Use in Pregnancy: During pregnancy, progesterone should only be used vaginally and restricted to the first trimester; there is a risk of undesirable effects on the liver during the second and third trimesters.