GynProgesterone Dosage/Direction for Use

Oral administration: In progesterone insufficiency the average dosage is from 200 to 300 mg micronised progesterone per day.
In pre-menstrual disorders, amenorrhea (primary & secondary) and bleeding due to fibroma, the usual treatment regimen is 200 to 300 mg per day: 200 mg in a single evening dose before going to bed, or 300 mg in 2 divided doses (200 mg before going to bed and 100 mg in the morning if necessary), 10 days per cycle, usually from the 17^th to the 26^th day inclusive.
In hormone replacement therapy in women receiving isolated estrogen there is an increased risk of endometrial cancer which should be countered by progesterone administration.
100 mg single dose can be given at bedtime from day 1 to day 25 of each therapeutic cycle, withdrawal bleeding being less with this treatment schedule.
200 mg single dose or 100 mg two doses during in the evening to bedtime, 12 to 14 days per month, or the last two weeks of each treatment sequence. This treatment must be followed by the total discontinuation of any replacement therapy for approximately one week during which a deprivation haemorrhage is often observed.
Vaginal administration: Supplementation of the luteal phase during IVF cycles: The recommended dosage is from 400 to 600 mg per day, in two to three divided doses, from the day of hCG injection up until the 12^th week of pregnancy.
Threatened miscarriage or prevention of habitual miscarriage due to luteal phase insufficiency: the recommended dosage is from 200 to 400 mg per day in two divided doses up until the 12^th week of pregnancy.
Preterm labour: Women with a history of preterm labour - 100 mg per day, given from 20 weeks of gestation until the risk of prematurity is low. Women with cervix shorter than 15 mm detected at 22-26 weeks - 200 mg per day until 36^th week of pregnancy.
Method of administration: Oral: take the capsules with a glass of water at the same time each day apart from mealtimes.
Vaginal: insert the capsules deep into the vagina by pushing them with a finger.