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Safe use of Zycloran in pregnancy has not been established. Some side effects such as jaundice and movement disorders have occurred in a few newborns exposed to the drug during the first trimester. Therefore, they should be administered cautiously to women of childbearing potential particularly during the first trimester of pregnancy and near term.
Zycloran is distributed into milk. Use with caution during lactation because of possible sedative and anticholinergic side effects on the infant.
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