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Symptoms: Parkinsonism, acute dystonias, somnolence, seizures, dry mouth, blurred vision, urinary retention, tachycardia, cardiac arrhythmias, hypotension, hypothermia or hyperthermia.
Treatment: Empty stomach using gastric lavage. Administer activated charcoal and a saline cathartic. Repeat activated charcoal and cathartic every 4 to 6 hrs to speed elimination. Support respiratory and cardiac functions as needed. Maintain fluid and electrolyte balance. Treat hypotension with i.v. fluids and by placing the patient in shock position. If unresponsive, dopamine may be required. Seizures may be treated with i.v. diazepam. Treat arrhythmias with phenytoin. Acute dystonic reactions may be treated with i.v. diphenhydramine, benztropine or trihexyphenidyl. Hemodialysis is ineffective. Hemoperfusion may be effective in severe cases but is usually not necessary.
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