Adults: Oral: In most patients oral treatment may be used from the start, commencing with a dosage of 25 to 50 mg three times daily and increasing as necessary: daily doses of 75 mg may be given as a single dose at night. In some patients doses of 10 mg three times daily may be adequate. Maintenance doses, when required usually range from 25 to 100 mg three times daily, although psychotic patients may require daily doses of up to 1 g or more. Doses of 10 to 25 mg every 4 to 6 hours are recommended for control of nausea and vomiting.
Initial doses of Zycloran of one-third to one-half the normal adult dose have been recommended for elderly and debilitated patients; doses should be increased more gradually.
Children: Oral: Ages 1-5 years may be given in a dose of 500 μg per kg body-weight every 4 to 6 hours. For psychiatric indications the oral dose for children aged over 5 years is usually one-third to one-half of the adult dose. Daily doses should not normally exceed 40 mg for children aged 1 to 5 years or 75 mg for children over 5 years of age.
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