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Usual Adult Dose: 200 mg (2 capsules) on the first day (as a single dose) or 100 mg (1 capsule) repeated after 12 hours, followed by 100 mg (1 capsule) daily.
Children above 8 years old weighing 45 kg or less: The usual dose is 4 mg/kg body weight in 2 divided doses initially (on the first day) followed by 2 mg/kg body weight daily. In severe infections, the initial dosage is maintained throughout the course of treatment.
Patients with sensitive gonococcal infections: 300 mg (3 capsules) as a single dose or followed by a second similar dose one hour later.
Patients with Syphilis: 200 mg (2 capsules) or 300 mg (3 capsules) daily for at least 14 or 10 days respectively.
Treatment of acne: 50 mg daily.
For relapsing fever and louse-borne typhus: 100 mg (1 capsule) or 200 mg (2 capsules) as a single dose.
For prophylaxis of scrub typhus: 200 mg (2 capsules) as a single dose.
For prophylaxis of leptospirosis: 200 mg once every 7 days. Prophylaxis should be initiated 1 to 2 days before exposure and continued throughout the period of exposure.
Or as prescribed by a physician.
