GENERAL: The colour of the vaccine may vary from orange-yellow to orange-red. Vaccine with a clearly yellow or violet colour cannot be used.
Since every dose can contain trace amounts of neomycin, streptomycin and polymyxin B, the administrator should be careful giving this vaccine to persons who are sensitive to these antibiotics.
Prior to an injection of any vaccine, all known precautions should be taken to prevent adverse reactions. This includes a review of the patient's history with respect to possible sensitivity to the vaccine or similar vaccines. Health-care providers should question the patient, parent or guardian about reactions to a previous dose of this product, or similar product.
Epinephrine Injection (1:1000) and other appropriate agents should be available to control immediate allergic reactions.
Health-care providers should obtain the previous immunization history of the vaccinee, and inquire about the current health status of the vaccinee.
Administration of Inactivated Poliomyelitis Vaccine (Types 1, 2 and 3) is not contraindicated in individuals infected with HIV. Special care should be taken to ensure that the injection does not enter a blood vessel.
USE IN CHILDREN: Safety and effectiveness of Inactivated Poliomyelitis Vaccine (Types 1, 2 and 3) in infants below six weeks of age has not been established.
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