Biogesic For Kids Drug Interactions

Do not use with any other medicine containing paracetamol (prescription or nonprescription). If the patient is not sure whether a medicine contains paracetamol, ask a doctor.
Prolonged use of paracetamol with other painkillers [e.g., drugs called nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin] is not recommended since it may increase the risk of toxic effects to the kidneys and eventually of kidney failure.
Chronic intake of alcohol may increase the risk of paracetamol-induced liver toxicity. Acute intake of alcohol may diminish the ability of the body to metabolize large doses of paracetamol. It is advised to consult a doctor before intake of paracetamol.
The absorption of paracetamol may be increased by metoclopramide or domperidone. Cholestyramine, narcotic pain relievers, and some antidepressants that slow down gastric emptying reduce the absorption of paracetamol. If the patient is taking these medicines, talk to the doctor first before taking paracetamol.
Medicines which stimulate the enzymes responsible for the metabolic activation of paracetamol such as medicines for convulsion (e.g., phenobarbital), depression (e.g., tricyclic antidepressants), and oral contraceptives may reduce the efficacy of paracetamol and increase susceptibility to the harmful effects to the liver.
Phenothiazines (medicines for serious mental and emotional disorder) may increase the risk of severe hypothermia (abnormally low body temperature).
Paracetamol increases exposure to chloramphenicol. This interaction should be considered when both medicines are given together in malnourished patients.
Probenecid may affect the elimination of paracetamol.
There may be an increased risk of bleeding when using paracetamol and warfarin (a blood thinning medicine) at the same time. Paracetamol, especially its prolonged regular use, increases the blood thinning effect of warfarin and other coumarins. If the patient is taking warfarin, ask the doctor first before taking paracetamol.
Tell the doctor if the patient is taking other medicines (especially other paracetamol-containing medicines), including vitamins, supplements, and herbal medicines.