Biogesic For Kids

Paracetamol

Relief of minor aches & pains due to the common cold, flu, sore throat, teething, headache, earache, post-immunization reactions, & toothache (for syr only). Fever reduction.

Max: Not to exceed 5 doses in 24 hr. Duration: Not to be used continuously for >5 days at a time. 120 mg/5 mL syr Childn 7-12 yr 10-15 mL every 4-6 hr, 3-6 yr 5-10 mL every 4-6 hr, 1-2 yr 5 mL every 4-6 hr. 250 mg/5 mL syr Childn 7-12 yr 5-7.5 mL every 4-6 hr, 3-6 yr 2.5-5 mL every 4-6 hr, 1-2 yr 2.5 mL every 4-6 hr. 100 mg/mL oral drops Childn 1-2 yr 1-1.2 mL every 4-6 hr. Infant 7 mth-<1 yr 1 mL every 4-6 hr, 4-6 mth 0.6-1 mL every 4-6 hr, 0-3 mth 0.3-0.6 mL every 4-6 hr.

May be taken with or without food.

Hypersensitivity. Patients receiving other medicines that contain paracetamol.

Discontinue use if symptoms of allergic reaction (eg, skin redness, blisters, or rash) occur; symptoms worsen or do not improve; new symptoms or any undesirable effect occur; redness or swelling is present; fever gets worse or lasts >3 days; pain gets worse or lasts >5 days in childn <12 yr & 10 days in adults; patient had unexpected bruising or bleeding, & had more infections than usual; sore throat is severe, persists for >2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting. Severe liver damage may occur if childn take >5 doses in 24 hr, or adult or child ≥12 yr take >4 g in 24 hr; in concomitant use w/ other medicines containing paracetamol. Patients w/ kidney or liver problems (including alcoholic liver disease); G6PD deficiency; whose illness whose cause is not clear or is accompanied by rash, breathing difficulties, diarrhea or excessive tiredness or lethargy; who are severely malnourished, anorexic, underwt, or excessively drink alcohol. Concomitant use w/ other painkillers or any other medicines.

Anemia, changes in the number of WBC & platelets eg, agranulocytosis, leukopenia, methemoglobinemia, neutropenia, pancytopenia, thrombocytopenia; thrombocytopenic purpura; allergic reactions which may cause difficulty swallowing, unexplained wheezing, shortness of breath or difficulty in breathing, skin rash, hives, or angioedema, proneness to infections, swelling around the eyes; hyperchloremia, hyperuricemia, loss of appetite, metabolic acidosis, sudden wt loss; headache; unusual bleeding or bruising; resp distress, runny nose, laryngeal edema; mouth ulcers, nausea, sore throat, vomiting; fixed eruption, itchy rash, severe skin reactions (ie, SJS, TEN, & acute generalized exanthematous pustulosis); chronic hepatic necrosis in prolonged use, liver dysfunction & injury, yellowing of eyes & skin; kidney toxicity, papillary necrosis in prolonged use; fatigue or unusual tiredness; decreased serum bicarbonate, Ca & Na; increases in serum alkaline phosphatase, glucose & transaminase levels.

Risk of toxic effects to the kidneys & eventually of kidney failure may be increased in prolonged use w/ other painkillers (eg, NSAIDs, aspirin). Risk of paracetamol-induced liver toxicity may be increased w/ chronic intake of alcohol. The ability of the body to metabolize large doses of paracetamol may be diminished w/ acute intake of alcohol. Absorption may be increased by metoclopramide or domperidone. Reduced absorption w/ cholestyramine, narcotic pain relievers, & some antidepressants that slow down gastric emptying. Efficacy may be reduced & susceptibility to the harmful effects to the liver may be increased w/ medicines which stimulate the enzymes responsible for the metabolic activation of paracetamol eg, medicines for convulsion (eg, phenobarb), depression (eg, TCAs), & OCs. May increase the risk of severe hypothermia w/ phenothiazines. Increased exposure to chloramphenicol. Elimination may be affected w/ probenecid. May increase risk of bleeding w/ warfarin.

Analgesics (Non-Opioid) & Antipyretics

N02BE01 - paracetamol ; Belongs to the class of anilide preparations. Used to relieve pain and fever.

Non-Rx