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APLOSYN-25 CREAM: Each g contains 250 mcg (0.025%) Fluocinolone acetonide in a water-washable aqueous base, with methyl and propyl paraben as preservatives.
APLOSYN-25 OINTMENT: Each g contains 250 mcg (0.025%) Fluocinolone acetonide in an ointment base.
APLOSYN-10 CREAM: Each g contains 100 mcg (0.01%) Fluocinolone acetonide in a water-washable aqueous base, with methyl and propyl paraben as preservatives.
APLOSYN-10 OINTMENT: Each g contains 100 mcg (0.01%) Fluocinolone acetonide in an ointment base.
APLOSYN OINTMENT is a mixture of wool fat, propylene glycol and white soft paraffin.
APLOSYN CREAMS employ a specially formulated hydrophilic base which is odorless, non-staining, and cosmetically appealing to the most particular patient. This finely micronized base provides quick release of the steroid facilitating onset of action. Its pH is close to that of the skin (5.6-5.7) thus preventing irritation and helping the skin renew and heal itself.
APLOSYN OINTMENT provides an emollient and water-protective base.
APLOSYN CREAMS and OINTMENTS provide maximum effectiveness and have shown no demonstrable risk of toxic reactions. The 0.01% and 0.25% Creams are more potent and significantly more effective than hydrocortisone 1.0% Cream. In relation to other corticosteroids used topically, APLOSYN has proved as effective as all and in many instances, effective even in cases where other agents gave an inadequate therapeutic response or other agents have failed. Numerous types of eczematous dermatoses which have not responded to other topical corticosteroids have been reported responsive to application of APLOSYN. With modified techniques of application, as mentioned below, highly refractory lesions such as those of psoriasis and other chronic dermatoses are amenable to treatment with APLOSYN. Repeated insult patch test of the base in the Creams, applied and reapplied to 200 patients over a total of three weeks, did not produce primary or allergic sensitivity. APLOSYN has the chemical formula 6α19α dilluoro - 16α hydroxyprednisolone 16, 17 acetonide. The cream has a water-washable aqueous base of stearic acid, with methyl and propylparaben as preservatives.
