Altrox Special Precautions

Alprazolam should be avoided in patients with pre-existing CNS depression or coma, respiratory depression, acute pulmonary insufficiency, myasthenia gravis, or sleep apnoea, and used with care in those with chronic pulmonary insufficiency. Alprazolam should be given with care to elderly or debilitated patients who may be more prone to adverse effects. Caution is required in patients with muscle weakness, or those with hepatic or renal impairment, who may require reduced doses; its use should be avoided in severe hepatic impairment.
The sedative effects of alprazolam are most marked during the first few days of use; affected patients should not drive or operate machinery. Monitoring of cardiorespiratory function is generally recommended when benzodiazepines are used for deep sedation.
Alprazolam is not appropriate for the treatment of chronic psychosis or for phobic or obsessional states. Alprazolam-induced disinhibition may precipitate suicide or aggressive behaviour and it should not, therefore, be used alone to treat depression or anxiety associated with depression; it should also be used with care in patients with personality disorders. Caution is required in patients with organic brain changes particularly arteriosclerosis. Dependence characterized by a withdrawal syndrome may develop after regular use of alprazolam, even in therapeutic doses for short; because of the risk of dependence, alprazolam should be used with caution in patients with a history of alcohol or drug addiction. Dependence may be also a particular problem at the high doses used in the treatment of panic attacks.
This product also contains FDC Yellow # 5 (Tartrazine) which may cause allergic-type reaction (including bronchial asthma) to certain susceptible person.