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During pregnancy, Votan should be employed only for compelling reasons and only in the lowest effective doses. As in the case of other prostaglandin-synthetase inhibitors, this applies particularly to the last 3 months of pregnancy (owing to the responsibility of uterine inertia and/or premature closure of the ductus arteriosus).
Following oral doses of 50 mg administered every 8 hours, the active substance passes into the breast milk, but in quantities so small that no desirable effects on the infant are to be expected.
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