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Adult An initial dose of 300-600 mg daily in divided doses, with 6-8 hours interval. Doses may increase to 12 g daily in initial control. Administered until patients reach euthyroid condition. Maintenance dose 100-300 mg in 3 divided doses. Thyrotoxic crisis 600-1200 mg in divided doses.
Children >10 years Initial dose 50-300 mg daily in divided doses, with 6-8 hours interval. Maintenance dose 100-300 mg daily in 2 divided doses with 2 hours intervals.
Children 6-10 years Initial dose 50-150 mg daily in divided doses, with 6-8 hours interval.
Neonatal Thyrotoxicosis 10 mg / kg BW.
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