Galtenix 300 Drug Interactions

There is no interaction between Gabapentin with phenobarbital, phenytoin, carbamazepine. Steady-state pharmacokinetic of Gabapentin is the same in healthy subjects and in patients with epilepsy who are receiving antiepileptic agents.
Concomitant use with oral contraceptives, including norethisterone and/or ethinylestradiol, will not affect the steady-state pharmacokinetics of each component.
Concomitant use with antacids can reduce the bioavailability of Gabapentin by up to 24%, but this is not clinically significant.
Renal excretion of Gabapentin is unaffected by probenecid. A slight reduction in Gabapentin excretion has been observed when administered together with cimetidine, which is not expected to be of clinical significance.