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In a study on fertility and early embryogenesis until implantation in rats, it has been reported that deciduation of sperm cells in seminiferous tubules was observed at doses of 200 mg/kg/day or more and atrophy/degeneration of seminiferous tubules as well as decreased sperm survival and sperm count were observed at a dose of 600 mg/kg/day.
Before starting treatment, the patient should be informed that occurrence of ejaculation with reduced or no semen may occur, temporarily affecting male fertility.
Use during pregnancy and lactation is not applicable as Silodosin is intended for male patients only.
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