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Posology: The adult dosage for oral use is 4 mg of silodosin twice daily after breakfast and evening meals. The dosage may be reduced according to the patient's conditions.
Precautions: The plasma concentration of silodosin may be elevated in patients with impaired hepatic function. It has been reported that plasma concentration of silodosin is increased in patients with impaired renal function. Therefore, starting treatment at a low dose (2 mg/dose) while observing the condition of the patient, for instance, should be considered. (See Pharmacology: Pharmacokinetics under Actions.)
Use in the Elderly: The elderly often have reduced physiological function. If hepatic or renal function is reduced, the elderly should be treated while carefully monitoring the condition of the patient, such as start administration at a low dose (2 mg/dose). (See Precautions.)
Use in Hepatic Impairment: As no data are available, the use in patients with severe hepatic impairment is not recommended.
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