Regivell Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

Concise Prescribing Info

Contents

Bupivacaine HCl

Indications/Uses

Spinal anesth for urological & lower limb surgery lasting 2-3 hr, abdominal surgery lasting 45-60 min.

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Dosage/Direction for Use

Adult Urological & lower limb surgery 1.5-3 mL. Abdominal surgery 2-4 mL.

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Contraindications

Known hypersensitivity to local anesth of amide type. Septicemia. Serious CNS disease eg, meningitis, poliomyelitis & cranial haemorrhage. Pyrogenic infection of the skin at or adjacent to puncture site. Severe shock. Coagulation disorder or ongoing anticoagulant treatment.

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Special Precautions

Hypotension, bradycardia. Paralysis of intercostals muscles. Consider preloading the circulation w/ crystalloidal or colloidal soln & treat w/ ephedrine IV, repeat as necessary. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Myocardial depression, hypotension, decreased cardiac output, bradycardia, ventricular arrhythmia; restlessness, anxiety, dizziness, drowsiness merging into unconsciousness & resp arrest; high or total spinal block, paralysis of lower extremities.

Drug Interactions

Combination w/ CNS depressants. Concurrent use w/ CYP3A4 inhibitors eg, azole antimycotic (ketoconazole), PIs (ritonavir), macrolides (erythromycin), Ca channel antagonists (verapamil) & CYP1A2 inhibitors eg, furafylline, clarithromycin.

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Storage

View Regivell storage conditions for details to ensure optimal shelf-life.

Description

View Regivell description for details of the chemical structure and excipients (inactive components).

Action

View Regivell mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Anaesthetics - Local & General

ATC Classification

N01BB01 - bupivacaine ; Belongs to the class of amides. Used as local anesthetics.

Thai FDA Category

Presentation/Packing

Form

Regivell inj 5 mg/mL

Packing/Price

4 mL x 5 × 1's

Regivell

bupivacaine

Manufacturer:

Novell Pharma

Distributor:

DKLL

Marketer:

Genemax Healthcare