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In the event of clinically significant constipation, treatment should be discontinued until normal bowel movement has resumed. Magnesium containing laxatives should not be used.
With oral administration, care should be taken to avoid aspiration, which may lead to bronchopulmonary complication.
Since effective lowering of serum potassium with calcium resin may take hours to days, treatment with this drug alone may be insufficient to rapidly correct severe hyperkalemia.
Patient monitoring: The following are recommended: 1. Serum calcium level, to detect the early development of hypercalcemia, weekly intervals.
The dose of resin is adjusted to prevent hypercalcemia and hypokalemia.
2. Serum magnesium levels, to detect hypomagnesemia.
Additional information: Treatment with calcium polystyrene sulfonate may be discontinued when the serum potassium concentrations have been reduced to 5 mEq (mmol) per litre.
