Adults: Oral: 15 g, divided into three or four times a day. The resin given by mouth as a suspension in a small amount of water (3 to 4 ml per g of resin), or it may be mixed with some sweetened vehicle (but not fruit juices, which contain potassium).
Rectal: In case of vomiting or upper gastro-intestinal problems, including paralytic ileus. The resin may be given rectally as a suspension of 30 g of resin in 150 ml of water or 10 percent dextrose in water, as a daily retention edema.
The enema should, if possible, be retained for at least 9 hours following which the colon should be irrigated to remove the resin.
If both routes are used initially, it is probably unnecessary to continue rectal administration once the oral resin has reached the rectum.
Children: Oral: Lower dose should be used; 1 mmol potassium per g of resin.
Initial dose: 1 g per kg of body weight daily in 3-4 divided doses.
Maintenance dose: 0.5 g per kg of body weight daily in 3-4 divided doses.
Rectal: Resin may be given rectally using a dose at least as great as that which would be given orally, diluted in the same ratio as described for adults.
Neonate: Should not be given by the oral route.
Rectal: 0.5 to 1 g per kg of body weight would be employed.
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