Kinelene Dosage/Direction for Use

Adult dosage: Oral administration: It is given orally, in a dose of 15 g three or four times daily.
Preparation for oral administration: Reconstituted KINELENE (POWDER FOR SUSPENSION 5 G) in 15-20 mL of water, syrup or sweetened paste (3-4 mL per 1 g of resin). Do not use fruit juices which contain potassium for reconstitution.
Rectal route: The usual daily dose is 30 g given as a suspension in 100 mL of 2% methylcellulose '450' and 100 mL of water and retained, if possible, for at least 9 hours. Initial therapy may involve both oral and rectal routes.
Following retention of the enema, the colon should be irrigated to remove the resin.
Children dosage: Oral administration: Dose for children is 1 g/kg daily in divided doses for acute hyperkalemia, reduced to a maintenance dose of 500 mg/kg daily in divided doses; the oral route is not recommended for neonates.
Rectal route: Children and neonates may be given rectal doses similar to the oral doses suggested for children.
Stability after reconstituted: Suspension of the resin should be freshly prepared. Suspension of KINELENE (POWDER FOR SUSPENSION 5 G) in 15-100 mL water is stable for 24 hours at room temperature (30°C) and stable for 48 hours at refrigerator temperature (2-8°C).
Dosage in geriatric: Refer to adult dosing.