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Film-coated tablet: No clinically relevant interactions were observed in clinical trials with desloratadine tablets in which erythromycin or ketoconazole were co-administered (see Pharmacology: Pharmacodynamics under Actions).
Pediatric population: Interaction studies have only been performed in adults.
In a clinical pharmacology trial, desloratadine tablets taken concomitantly with alcohol did not potentiate the performance impairing effects of alcohol (see Pharmacology: Pharmacodynamics under Actions). However, cases of alcohol intolerance and intoxication have been reported during post marketing use. Therefore, caution is recommended if alcohol is taken concomitantly.
Syrup: There was no effect of food or grapefruit juice on the disposition of desloratadine. DESTA SYRUP taken concomitantly with alcohol did not potentiate the performance impairing effects of alcohol.
