Avoid use in patients consuming >2 drinks of alcohol daily; w/ serious infection; recently undergone organ transplant; serious disease or physical disorder or recently undergone major surgery. Advise patients to periodically test for SGPT & creatine kinase for long-term use. May cause mild GI upset that can be alleviated if taken after meals. Not recommended for individuals at risk for or having history of liver disease. Not recommended for individuals <20 yr.