Warfarin is used in the prevention and treatment of venous thromboembolism, systemic thromboembolism and ischaemic stroke in some patients with atrial fibrillation, prosthetic heart valves or who have suffered a myocardial infarction. It may also have a role in the prevention of myocardial infarction and in the management of stroke or transient ischaemic attacks. Antiplatelet drugs may be given concomitantly.