Tozam Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Losartan K 50 mg, amlodipine besilate 5 mg

Indications/Uses

Mild to moderate HTN in case of inadequate control of monotherapy.

Click to view Tozam detailed prescribing information

Dosage/Direction for Use

1 tab once daily.

Click to view Tozam detailed prescribing information

Overdosage

View Tozam overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food: Swallow whole, do not chew/crush.

Contraindications

Patients allergic to angiotensin receptor blocker or dihydropyridine Ca-channel antagonist.

Click to view Tozam detailed prescribing information

Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Tozam detailed prescribing information

Special Precautions

Symptomatic hypotension in patients w/ vol- &/or salt depletion. Discontinue therapy if patient developed jaundice or marked elevations of hepatic enzymes. Impaired liver & renal function. Pregnancy & lactation. Childn & adolescent <18 yr.

Click to view Tozam detailed prescribing information

Use In Pregnancy & Lactation

Click to view Tozam detailed prescribing information

Adverse Reactions

Losartan K: Diarrhea, dyspepsia; muscle cramp, myalgia, back & leg pain; dizziness, insomnia; nasal congestion, cough, upper resp tract infection, sinus disorder, sinusitis. Amlodipine besilate: Edema, flushing, palpitation, fatigue, headache, somnolence, abdominal pain, dizziness.

Drug Interactions

Losartan K: Increase AUC w/ cimetidine. Potent inducers of CYP3A4. Increase in serum K w/ K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or salt substitutes containing K.

Click to view Tozam detailed prescribing information

Storage

View Tozam storage conditions for details to ensure optimal shelf-life.

Description

View Tozam description for details of the chemical structure and excipients (inactive components).

Action

View Tozam mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Angiotensin II Antagonists / Calcium Antagonists

ATC Classification

C09DB06 - losartan and amlodipine ; Belongs to the class of angiotensin II receptor blockers (ARBs) and calcium channel blockers. Used in the treatment of cardiovascular disease.

Regulatory Classification

Presentation/Packing

Form

Tozam FC tab

Packing/Price

100's (P2,860/pack)

Tozam

amlodipine + losartan

Manufacturer:

Torrent

Distributor:

Torrent