Each vial contains Cefuroxime sodium 750 mg.
Used in the treatment of susceptible infections.
These have included bone and joint infections, bronchitis, gonorrhea, meningitis (although treatment failures have been reported in H. influenza meningitis), otitis media, peritonitis, pharyngitis, sinusitis, skin infections (including soft-tissue infections), and urinary tract infections, it is also used for surgical infection prophylaxis.
Adult: 750 mg-1.5 g 6-8 hourly. Children: 75-150 mg/kg/day in divided doses.
Intramuscular injection: Add 3ml of water for injection to 750mg. Shake gently to produce a suspension.
Add 6ml of water for injection to 1.5g. Shake gently to produce a suspension.
Intravenous administration: Dissolve Cefuroxime in water for injection using at least 6ml for 750mg. Shake gently to produce a suspension.
Dissolve cefuroxime in water for injection using at least 15ml for 1.5g.
Hypersensitivity to any of the cephalosporins.
Penicillin-sensitive patients, gastrointestinal disease especially colitis. Monitor kidney function. Prolonged treatment. Pregnancy and lactation. Children below 3 months.
Pain at intramuscular injection site, thrombophlebitis after intravenous administration. Pseudomembranous colitis, leukopenia, thrombocytopenia, positive Coombs test. Hypersensitivity reactions eg, rash, urticaria and anaphylaxis.
Increased nephrotoxicity with probenecid, ethacrynic acid, furosemide, gentamycin and vancomycin. Disulfiram-like reaction with alcohol ingestion with cephalosporins with methyltetrazole-thiol (MTT) side chain; e.g. cefamandole, cefoperazone, moxalactam and cefotetan. High dose heparin, oral anticoagulants and other drugs that affect hemostasis. May increase the risk of hemorrhage with cephalosporins with MTT side chain. Potent diuretics.
Store at temperatures not exceeding 30°C.
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Roxicef powd for inj 750 mg
(vial + 10 mL amp diluent) 1's
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