Adult & childn ≥40 kg Community acquired pneumonia, acute exacerbations of chronic bronchitis, cellulitis, erysipelas, wound infection, intra-abdominal infection 750 mg IV/IM every 8 hr.
Complicated UTI, including pyelonephritis 1.5 g IV/IM every 8 hr.
Severe infection 750 mg IV every 6 hr, or 1.5 g IV every 8 hr.
Surgical prophylaxis for GI, gynaecological surgery (including caesarean section) & orthopedic operation 1.5 g w/ anaesth induction. May be supplemented w/ two 750 mg IM doses after 8 hr & 16 hr.
Surgical prophylaxis for CV & oesophageal operation 1.5 g w/ induction of anaesth followed by 750 mg IM every 8 hr for a further 24 hr.
Childn <40 kg, infant & toddler >3 wk Community acquired pneumonia, complicated UTI (including pyelonephritis), cellulitis, erysipelas, wound infection, intra-abdominal infection 30-100 mg/kg/day IV given as 3 or 4 divided doses.
Infant (birth to 3 wk) 30-100 mg/kg/day IV given as 2 or 3 divided doses.
Patient w/ renal impairment, CrCl 10-20 mL/min/1.73 m2 750 mg bid,
CrCl <10 mL/min/1.73 m2 750 mg once daily.
Patient on haemodialysis A further 750 mg IV/IM dose should be given at the end of each dialysis. Additionally, cefuroxime Na can be incorporated into peritoneal dialysis fluid (usually 250 mg for every 2 L of dialysis fluid).
Patient w/ renal failure on continuous arteriovenous haemodialysis or high-flux haemofiltration 750 mg bid. For low-flux haemofiltration, follow dose recommendation under patient w/ renal impairment.
Sign Out
