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Incompatibilities: In general, mixing Gentamicin Injection with other drugs prior to administration is not in particular advised. The following are incompatible in mixed solution with Gentamicin Injection: penicillins, cephalosporins, erythromycin, lipiphysan, heparins and sodium bicarbonate. In the latter case carbon dioxide may be liberated on addition of the two solutions. Normally this will dissolve in the solution, but under some circumstances small bubbles may form.
Dilution in the body will obviate the danger of physical and chemical incompatibility and enable Gentamicin Injection to be given concurrently with the drugs listed previously either as a bolus injection into the drip tubing, with adequate flushing, or at separate sites. However, in the case of carbenicillin and gentamicin they should only be given at separate sites.
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