Rocygen Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Gentamicin sulfate

Indications/Uses

Bacteremia, septicemia, UTI, severe chest infections & other systemic infections due to susceptible bacteria.

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Dosage/Direction for Use

Adult 3-4 mg/kg daily in divided doses. Typical doses: ≥60 kg 80 mg 8 hrly, <60 kg 60 mg 8 hrly. Renal impairment CrCl >70 mL/min 80 mg 8 hrly, 30-70 mL/min 80 mg 12 hrly, 10-30 mL/min 80 mg daily, 5-10 mL/min 80 mg every 48 hr, <5 mL/min 80 mg after dialysis. UTI 160 mg once daily. Increase dose to 6 hrly or for a total dose of 5 mg/kg in 24 hr in cases of life-threatening infections. Childn up to 12 yr 2 mg 8 hrly. Infant up to 2 wk 3 mg 12 hrly.

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Overdosage

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Contraindications

Hypersensitivity. Myasthenia gravis.

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Special Precautions

Impaired renal function. Assess CrCl rates or blood urea. Check serum levels to confirm that peak (1 hr) levels do not exceed 10 mcg/mL & trough levels (before next inj) do not exceed 2 mcg/mL. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Nephrotoxicity.

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Drug Interactions

Potential increase of nephrotoxicity w/ cephalosporins. May potentiate ototoxicity w/ furosemide, piretanide & ethacrynic acid. Reduced activity w/ ticarcillin. Neuromuscular blockade & resp paralysis w/ curare-type muscle relaxants during anesth. Antagonism w/ bacteriostatic antibiotics.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Rocygen detailed prescribing information

Storage

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Description

View Rocygen description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Aminoglycosides

ATC Classification

J01GB03 - gentamicin ; Belongs to the class of other aminoglycosides. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Rocygen soln for inj 40 mg/mL

Packing/Price

2 mL x 10 × 1's

Rocygen

gentamicin

Manufacturer:

Rotexmedica GmbH

Distributor:

Duopharma Trade (Phils)