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In the treatment of hypertension: the initial dose is 1.25 mg once daily. The usual maintenance is 2.5 mg to 5 mg daily, although up to 10 mg daily maybe required or as prescribed by the physician.
In the management of heart failure: the initial dose is 1.25 mg once daily. The usual maximum dose is 10 mg daily; doses of 2.5 mg or more daily may be taken to 1 or 2 divided doses. Or as prescribed by the physician.
For myocardial infarction: the usual the initial dose is 2.5 mg or more daily maybe taken to 1 or 2 divided doses. Or as prescribed by the physician.
For the prophylaxis of cardiovascular events: the initial dose is 2.5 mg once daily. The dose should be increased, if tolerated, to 5 mg once daily after 1 week, then to the usual maintenance dose of 10 mg once daily after further 3 weeks. Or as prescribed by the physician.
In patients with hypertension or recent myocardial infarction it may also be given in divided doses.
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