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Neuro-B's/Neuro-B's 500

Neuro-B's/Neuro-B's 500 Mechanism of Action

Manufacturer:

Drugmaker's Lab

Distributor:

Pharma Dynamic
Full Prescribing Info
Action
Neuro-B's: Vitamin B replacement: Vitamin B1 and B6 constitute part of an enzyme system in the nerve cell and are necessary for normal function of nerve tissue. They are used in the treatment of neurological disorders associated with nerve cell dysfunction. Vitamin B12 is necessary for the synthesis of nucleic acid in the erythropoiesis and plays an important role in the metabolism of the nerve tissue.
Neuro-B's 500: Pharmacology: Pharmacokinetics: Thiamine Mononitrate (Vitamin B1) in small amounts are well absorbed from the gastrointestinal tract but absorption of dose larger than about 5 mg is limited. It is widely distributed to most body tissues, and appears in breast milk. Thiamine is not stored to any appreciable extent in the body and amounts in excess of the body's requirements are excreted in the urine as unchanged thiamine or as metabolites.
Pyridoxine Hydrochloride (Vitamin B6) is readily absorbed from the gastrointestinal tract and is converted to the active forms pyridoxal phosphate and pyridoxamine phosphate which are mainly stored in the liver. These are oxidized into 4-pyridoxic acid and other inactive metabolites which are excreted in the urine.
Cyanocobalamin (Vitamin B12) binds to intrinsic factor and is then actively absorbed from the gastrointestinal tract. Absorption is impaired in the absence of the intrinsic factor, with a malabsorption syndrome, with the disease or abnormality in the gut, or after gastrectomy. Cyanobalamin is stored in the liver, excreted in the bile, and undergoes extensive enterohepatic recycling; part of an administered dose is excreted in the urine, most of it in the first 8 hours.
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