Medyclin Dosage/Direction for Use

Dosage in Adults: 600-1800 mg/day divided in 2, 3 or 4 equal doses. To avoid the possibility of esophageal irritation, clindamycin HCl capsules should be taken with a full glass of water.
Dosage in Children (over 1 month of age): Clindamycin hydrochloride capsules (for children who are able to swallow capsules): To avoid the possibility of esophageal irritation, clindamycin HCl capsules should be taken with a full glass of water.
Doses of 8-25 mg/kg/day in 3 or 4 equal doses.
Clindamycin capsules are not suitable for children who are unable to swallow them whole.
Dosage in Elderly: Pharmacokinetic studies with clindamycin have shown no clinically important differences between young and elderly subjects with normal hepatic function and normal (age-adjusted) renal function after oral administration. Therefore, dosage adjustments are not necessary in the elderly with normal hepatic function and normal (age-adjusted) renal function.
Dosage in Renal Impairment: Clindamycin dosage modification is not necessary in patients with renal insufficiency.
Dosage in Hepatic Impairment: Clindamycin dosage modification is not necessary in patients with hepatic insufficiency.
Dosage in Specific Indications: Treatment of Beta-Hemolytic Streptococcal Infections: Refer to the dosage recommendations previously mentioned under Dosage in Adults and Dosage in Children. Treatment should be continued for at least 10 days.
Treatment of Chlamydia trachomatis Cervicitis: Clindamycin hydrochloride capsules orally 450-600 mg 4 times daily for 10-14 days.
Treatment of Toxoplasmic Encephalitis in Patients with AIDS: Clindamycin hydrochloride orally 600-1200 mg every 6 hours for 2 weeks followed by 300-600 mg orally every 6 hours. The usual total duration of therapy is 8 to 10 weeks.
Treatment of Pneumocystis carinii Pneumonia in Patients with AIDS: Clindamycin hydrochloride 300 to 450 mg orally every 6 hours for 21 days.
Treatment of Acute Streptococcal Tonsillitis/Pharyngitis: Clindamycin hydrochloride capsules 300 mg orally twice daily for 10 days.