Adult & childn >12 yr or weighing ≥40 kg 375 mg every 8 hr. More severe & resp tract infections 625 mg every 8 hr. Dental infections 375 mg every 8 hr for 5 days.
View Lox overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food: Preferably taken at the start of meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity or allergic reactions including shock to amoxicillin, clavulanic acid or β-lactams (penicillin, cephem) drugs. Patients w/ accompanying infection of virus diseases eg, infectious mononucleosis & lymphocytic leukemia; history of amoxicillin/clavulanate K- or penicillin-associated jaundice or hepatic dysfunction (possible recurrence). Pregnancy (1st trimester).
Severe hepatic dysfunction; moderate or severe renal disorder. Family history or known susceptibility to allergic symptoms eg, bronchial asthma, rashes, urticaria; poor oral intake or general condition (vit K deficiency) on parenteral nutrition; GI diseases w/ vomiting or diarrhea, K & Na restricted diet. Avoid prolonged use (>14 days) & when infectious mononucleosis occurs. Hypersensitivity (anaphylactic) reactions & angioedema, (rare) anaphylactic shock, moderate to severe pseudomembranous colitis. Discontinue use if symptoms eg, urticaria, skin rash & serum diseases occur. Regularly monitor hematopoiesis, renal & hepatic function. False +ve reactions for Clinitest, Benedict's or Fehling's soln. Influence result in urobilinogen tests & +ve Coombs' test. Lactation. Childn, premature babies & infants <2 mth. Elderly.
J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
Sign Out
