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Adults: Adapalene Microspheres + Clindamycin Phosphate Gel is used in the topical treatment of mild to moderate acne where comedones, papules and pustules predominate. Adapalene Microspheres Plus Clindamycin Phosphate Gel is applied once daily at night to the skin that that has been cleansed and dried. Other topical preparations that may cause irritation should not be used concomitantly.
During the early weeks of therapy, an apparent exacerbation of acne may occur. This is due to the action of the medication on previously unseen lesions and should not be considered a reason to discontinue therapy. Therapeutic results should be noticed after eight to twelve weeks of treatment.
Pediatric Population: The safety and efficacy of Adapalene Microspheres + Clindamycin Phosphate Gel in pediatric patients under the age of 12 years have not been established.
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