Hemoclot (Tranexamic Acid) is a white crystalline powder, odorless, has a bitter taste encapsulated in empty gelatin capsule size #0 with brown op. cap and yellow op. body.
Each capsule contains: Tranexamic Acid, USP 500 mg.
Pharmacology: Pharmacodynamics: Tranexamic Acid is an anti-fibrinolytic agent. It acts principally by inhibiting plasminogen activators.
Pharmacokinetics: Tranexamic Acid is rapidly absorbed from the gastrointestinal tract. Up to about 30% of the dose by mouth and at least 90% of the dose by intravenous injection is reported to be excreted in the urine within 24 hours. It diffuses across the placenta.
Used in the treatment of hemorrhage, or threatened hemorrhage, associated with excessive fibrinolysis. It is many times more potent than aminocaproic acid.
1 to 1.5 g or 15 to 25 mg per body weight 2 to 3 times a day to be given by mouth. Theses doses should be reduced in patients with renal impairment.
There are limited data on tranexamic acid overdosage. Symptoms may include dizziness, headache, nausea, vomiting, diarrhea, hypotension, or orthostatic hypotension.
There is no known antidote for tranexamic acid overdose. In cases of overdose, discontinue treatment.
Tranexamic Acid is contraindicated in patients with active intravenous clotting and caution is necessary in any condition which may predispose to thrombosis. Use in disseminated intravascular coagulation is potentially dangerous and may result in serious thrombosis. If tranexamic acid has to be used in this condition, it should be accompanied by heparin. Tranexamic acid should be withdrawn if patient develops muscle pain or weakness.
Tranexamic Acid is considered to be better tolerated than aminocaproic acid. Patients may experience nausea, vomiting, or diarrhea. There may be a hypotensive reaction to rapid intravenous administration. Like aminocaproic acid, there is a risk of the lysis of existing clots being inhibited, unlike its myopathy does not appear to be a problem.
Store at a temperature not exceeding 30°C.
B02AA02 - tranexamic acid ; Belongs to the class of amino acid antifibrinolytics. Used in the treatment of hemorrhage.
Hemoclot cap 500 mg
100's
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