Tranexamic Acid is contraindicated in patients with active intravenous clotting and caution is necessary in any condition which may predispose to thrombosis. Use in disseminated intravascular coagulation is potentially dangerous and may result in serious thrombosis. If tranexamic acid has to be used in this condition, it should be accompanied by heparin. Tranexamic acid should be withdrawn if patient develops muscle pain or weakness.