Gretor 90 Dosage/Direction for Use

Ticagrelor tablets can be taken with or without food.
Ticagrelor 90 mg: In the management of ACS, initiate ticagrelor tablets treatment with a 180 mg loading dose (two tablets of 90 mg). Administer 90 mg twice daily during the first year after an ACS event. After one year, administer 60 mg twice daily. Use ticagrelor tablets with a daily maintenance dose of aspirin of 75 to 100.
Do not administer ticagrelor tablets with another oral P2Y₁₂ platelet inhibitor. For patients who are unable to swallow tablets whole, ticagrelor tablets can be crushed, mixed with water and drunk. The mixture can also be administered via a nasogastric tube (CH8 or greater). A patient who misses a dose of ticagrelor tablets should take one tablet (their next dose) at its scheduled time. Premature discontinuation with antiplatelet therapy could result in an increased risk of cardiovascular (CV) death, myocardial infarction (MI), or stroke due to the patient's underlying disease. Physicians who desire to switch patients, with prior ACS event, to Ticagrelor should administer the first dose of Ticagrelor 24 hours following the last dose of the other anti-platelet medication.